| Title | Maintaining quality of life – Electrochemotherapy for palliative periocular malignancy |
| Submitted by | Katja Ullrich |
| Abstract Number | 321 |
| 19-188 | |
| Review Result | poster presentation |
| Purpose | Electrochemotherapy (ECT) has been used successfully for treatment of recurrent head and neck cancers. We report four cases of metastatic periocular tumours that were treated palliatively with ECT. |
| Methods | Case series of 4 palliative patients with widespread metastatic malignancy and periocular involvement. All patients were offered surgical resection but preferred less involved measures. We report technique and outcomes. |
| Results | 83 year-old man with metastatic malignant melanoma (MM) including nodules in the right medial orbit and medial canthus. After ECT treatment, he was able to open his eye again, the nodules decreased in size and he had less pain. 72 year-old man with metastatic MM. He had painful metastatic nodules on the forehead and the left medial canthus. After ECT, he had initially increasing pain due to tumour necrosis for 3 days, then significant pain relief. 93 year-old man with widespread palliative multiple myeloma and left forehead SCC, causing pain due to perineural invasion. He underwent ECT treatment, resulting in pain relief and shrinkage of the SCC. 91 year-old woman with lower eyelid sebaceous cell carcinoma. She previously underwent excision with 4mm clearance and negative conjunctival map biopsies. She failed to attend multiple appointments and returned with loco-regional recurrence and lymph node metastasis. After refusing further workup, underwent ECT to decreased the size of her lower lid tumor mass. 3 patients have died due to their disease. All experienced an improvement in their pain. None of the patients developed significant periocular inflammation. |
| Conclusion | Electrochemotherapy may be a useful palliative treatment for periocular tumors to improve pain and reduces tumour volume. |
Additional Authors
| Last name | Initials | City / Hospital | Department |
|---|---|---|---|
| Bisase | B | Queen Victoria Hospital NHS Foundation Trust | Plastic Surgery |
| Kumar | S | Queen Victoria Hospital NHS Foundation Trust | Plastic Surgery |
| Malhotra | R | Queen Victoria Hospital NHS Foundation Trust | Corneoplastics Unit |
