View 2019 Abstracts

Title Methodology of functional lacrimal MRI imaging
Submitted by Valerie Juniat
Abstract Number 106
Review Result rapid fire presentation
Purpose

Functional epiphora is a common and poorly understood condition. Dacryocystogram and dacryscintigraphy are variably used to investigate it but have major limitations with physiological and anatomical information respectively. We describe the use of dynamic magnetic resonance dacryocystography (MRDCG) to provide functional video images of the lacrimal drainage system.

Methods

15 volunteers with no lacrimal symptoms and 5 patients with unilateral epiphora were prospectively recruited and underwent dynamic MRDCG. Dotarem contrast agent (Gadoteric acid 0.5 mmol/mL) was diluted 50 folds in sterile normal saline and infused from an Alaris GH Syringe Pump machine (infusion rate of 3mls/h) through a cannula onto the patient’s eyes. The volumetric interpolated breath-hold examination (VIBE) sequence was used to visualise contrast flow through the lacrimal drainage system on a 1.5T MRI scanner.

Results

Dynamic MRDCG with VIBE provides videos that reliably demonstrate contrast flow that is physiological and gives good anatomical data.

Conclusion

Dynamic MRDCG provides good structural and temporal resolution of tear flow. It has the potential to be used as a routine clinical investigation of patients with epiphora that can safely and quickly provide functional and anatomical information of the tear drainage system and surrounding region. This may help understand the cause and guide the treatment of lacrimal drainage disease.


Additional Authors
Last name Initials City / Hospital Department
Kazempour Y Sussex Eye Hospital Ophthalmology
Sia P Royal Adelaide Hospital Ophthalmology
Selva D Royal Adelaide Hospital Ophthalmology
Harris L Brighton and Sussex University Hospitals Radiology
Lewis H Brighton and Sussex University Hospitals Radiology
Martin J Brighton and Sussex University Hospitals Radiology
Rajak S Sussex Eye Hospital Ophthalmology